Endocrine Abstracts

Objective: Patients with Cushing’s disease (CD) may have adrenal nodules or hyperplasia related chronic hyperstimulation by adrenocorticotropic hormone (ACTH). The aim of this study was to describe the prevalence of adrenal nodules or hyperplasia in patients with CD and their relation with ACTH levels at diagnosis.Patients and methods: Descriptive study of patients with CD (1995–2015). Variables analyzed: age, sex, body mass in...

Introduction: Even though pituitary apoplexy usually occurs in the context of a pituitary adenoma, it can also occur over other tumours, which is less common in adulthood and has faster growth and aggressiveness. It can also produce clinical, analytical and even radiological indications that are indistinguishable from a pituitary adenoma with ischemic and/or haemorrhagic events.Case report: A 43-year-old female, with no medical history of interest except...

The 46 XX male syndrome (de la Chapelle syndrome or 46,XX testicular disorder of sex development -46,XX testicular DSD-) is a rare phenotype associated with disorder of the sex chromosomes. XX males exist in different clinical categories with ambiguous genitalia or partially to fully mature male genitalia, in combination with complete or incomplete masculinization.Clinical report: We describe the clinical, molecular, and cytogenetic findings of a 26-year...

Objective: Relationship between pre-pregnancy BMI (PPBMI) in gestational diabetic (GD) patients, and age, country of origin, family history of type 2 diabetes mellitus (T2DM), GD history, and BMI after pregnancy.Methods: Transversal, descriptive study of 259 consecutive pregnant with confirmed DG. Analysis were based on Fisher’s exact test and Student’s t-test. A P<0.05 was significant (SPSS 19.0).Re...

Objective: Our objective in this study was to identify the type of clinical care received by young type 1 diabetic patients who have made the transition from paediatric to adult care, and to assess the metabolic status of the patients. The research aimed to develop a sustainable and coordinated approach to facilitating the transition between diabetes services for adolescents and reveal from the perspective of the adolescents living with type 1 diabetes their experiences surrou...

Objective: We retrospectively analyzed patients with type 1 diabetes onset, attended during the years 2005 and 2006 on the specific query of type 1 DM debut of a tertiary hospital, with initial treatment assessment, at 1 and 5 years evolution.Results: Patients were treated for newly diagnosed DM 1, 25 patients (72% male, 28% female) mean age 23.2 years (14–36), mean BMI: 23.18 (18–33.8%).The clinical presentation included: 88.24% presented with...

Objective: To evaluate in our area BICI therapy efficacy in pregestational type 1 diabetes.Methods: We conducted a descriptive retrospective analysis studying metabolic control and obstetrics results in patients with pregestational type 1 diabetes, treated with BICI between 2004 and 2012 in our hospital.Results: We evaluated 28 patients with type 1 diabetes and diabetes duration of 17.3±6.6 years. In 27.3% of patients the trea...

Objective: To evaluate continuous subcutaneous insulin infusion (CSII) in type 1 diabetes using the analysis of epidemiological variables, treatment indications, metabolic results, acute and chronic complications and causes for therapy suspension.Methods: A retrospective descriptive study of patients with type 1 diabetes treated with CSII therapy in our institution.Results: A total of 49 type 1 diabetic patients who had been treate...

Introduction: Pheochromocytomas (Pheo) may appear sporadically (SPheo) or as an autosomal dominant inherited disease, named as familial PHEOs (FPheo). The latter are present in younger patients, and usually with multiple tumors, but may occur in patients with apparently simple sporadic tumors with no other syndromic features.Material and methods: Clinical data of all consecutive patients underwent surgery for Pheo over 35 years in two tertiary referral c...

Introduction: In type 2 diabetes the choice of the second drug after metformina is marked by the basic characteristics of the patient.Objetive: To analyze in real clinical practice the effectiveness of different antidiabetics.Material and methods: Observational study including patients with type 2 diabetes, in which we added to metformina different antidiabetics. We revised them 3-6 months from change.Results...